Potentiating action of hexoprenaline on 14C-aminopyrine uptake by isolated rat parietal cells
- PMID: 6723912
- DOI: 10.1007/BF01952394
Potentiating action of hexoprenaline on 14C-aminopyrine uptake by isolated rat parietal cells
Abstract
Hexoprenaline potentiated the 14C-aminopyrine uptake (a reliable index of H+ generation) of isolated rat gastric cells stimulated by 10(-6) -10(-4) mol/l carbachol, and inhibited that in response to 10(-4) mol/l histamine without and in the presence of propranolol. It is concluded that hexoprenaline acts as a partial agonist on parietal cell H2-receptors and that beta-adrenoceptor activation may functionally modulate gastric acid secretion.