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Serum inhibitor in systemic lupus erythematosus associated with aplastic anemia
- PMID: 6732407
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Case Reports
Serum inhibitor in systemic lupus erythematosus associated with aplastic anemia
Arch Intern Med.
1984 Jul.
Abstract
Hematologic complications of systemic lupus erythematosus (SLE) usually involve peripheral destruction of blood elements. We report a case of SLE-associated aplastic anemia in which an IgG complement-dependent antibody, obtained from the patient's disease-phase serum but not remission-phase serum, suppressed growth of granulocyte-macrophage progenitor cells from bone marrow of normal donors in vitro. Therapy with plasmapheresis and immunosuppression resulted in lasting remission.
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