Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1984 Apr 15;219(2):539-46.
doi: 10.1042/bj2190539.

Species differences in the occurrence of copper-metallothionein in the particulate fractions of the liver of copper-loaded animals

R K Mehra, I Bremner
Comparative Study

Species differences in the occurrence of copper-metallothionein in the particulate fractions of the liver of copper-loaded animals

R K Mehra et al. Biochem J. .

Abstract

Large amounts of Cu-metallothionein were obtained by 2-mercaptoethanol and sodium dodecyl sulphate extractions of the particulate fractions of the liver of pigs given high-Cu2+ diets or rats injected with Cu2+. Three isoproteins were purified from pig liver and characterized on the basis of their physicochemical properties, metal content and amino acid composition. No such pool of Cu-metallothionein was present in the liver of Cu2+-loaded sheep or of rats given Cu2+-supplemented diets.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Am J Pathol. 1968 Dec;53(6):883-901 - PubMed
    1. Nature. 1970 Oct 10;228(5267):172-3 - PubMed
    1. Br J Nutr. 1970 Dec;24(4):989-1003 - PubMed
    1. Toxicol Appl Pharmacol. 1971 Mar;18(3):562-72 - PubMed
    1. Biochem Biophys Res Commun. 1974 Feb 4;56(3):661-8 - PubMed

Publication types