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. 1984;67(2):214-5.
doi: 10.1007/BF00273004.

The Cd technique identifies a specific structure related to centromeric function

S Lambiase, P Maraschio, O Zuffardi

The Cd technique identifies a specific structure related to centromeric function

S Lambiase et al. Hum Genet. 1984.

Abstract

The evidence that the Cd technique identifies the kinetochore was based on the finding that inactive centromeres are C-positive but Cd-negative. The identity between Cd-positivity and centromere function is now confirmed by the reverse procedure: a stable abnormal chromosome is consistently C-negative but Cd-positive at its single centromeric constriction. This demonstrates that the Cd dots are not a relic of C-banding but identify the active centromere.

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