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. 1984 Aug;99(2):373-7.
doi: 10.1083/jcb.99.2.373.

The eucaryotic aminoacyl-tRNA synthetase complex: suggestions for its structure and function

M P Deutscher

The eucaryotic aminoacyl-tRNA synthetase complex: suggestions for its structure and function

M P Deutscher. J Cell Biol. 1984 Aug.

Abstract

Aminoacyl-tRNA synthetases from eucaryotic cells generally are isolated as high molecular weight complexes comprised of multiple synthetase activities, and often containing other components as well. A model is proposed for the synthetase complex in which hydrophobic extensions on the proteins serve to maintain them in their high molecular weight form, but are not needed for catalytic activity. The structural similarity of these enzymes to certain membrane-bound proteins, and its implications for synthetase localization and function in vivo, are discussed.

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References

    1. Biosci Rep. 1983 Jun;3(6):527-38 - PubMed
    1. EMBO J. 1982;1(6):733-6 - PubMed
    1. Proc Natl Acad Sci U S A. 1971 May;68(5):1042-6 - PubMed
    1. Eur J Biochem. 1971 May 28;20(2):283-300 - PubMed
    1. J Mol Biol. 1971 Aug 28;60(1):113-22 - PubMed

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