Transfer of tetracycline or clindamycin resistance among strains of Bacteroides fragilis in experimental abscesses
- PMID: 6747344
- DOI: 10.1093/infdis/150.1.20
Transfer of tetracycline or clindamycin resistance among strains of Bacteroides fragilis in experimental abscesses
Abstract
The ability of strains of Bacteroides fragilis resistant to clindamycin and/or tetracycline to transfer resistance to a susceptible recipient strain in experimental subcutaneous abscesses in mice was investigated. The results indicated that such transfer took place at a frequency similar to that observed in vitro. Transfer of resistance determinants at infected sites may play a role in the epidemiology of disseminated resistance to antimicrobial agents.
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