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. 1982 Aug;16(2):408-10.
doi: 10.1128/jcm.16.2.408-410.1982.

Serotype B/C Cryptococcus neoformans isolated from patients in nonendemic areas

R A Fromtling, S Shadomy, H J Shadomy, W E Dismukes

Serotype B/C Cryptococcus neoformans isolated from patients in nonendemic areas

R A Fromtling et al. J Clin Microbiol. 1982 Aug.

Abstract

Of 90 clinical isolates of Cryptococcus neoformans studied, 3 were determined to be serotype B/C. The patients from whom these B/C isolates were obtained were identified as never having lived in or visited the areas associated with B/C serotypes. This finding suggests a broader geographic distribution of this serotype group than previously believed. The glycine-cycloheximide-phenol red medium described by Salkin and Hurd (J. Clin. Microbiol. 15:169-171, 1982) was shown to be more accurate in differentiating A/D and B/D serotype pairs of C. neoformans than the creatinine-dextrose-bromthymol blue medium described by Kwon-Chung et al. (Int. J. Syst. Bacteriol. 28:616-620, 1978).

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