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Clinical Trial
. 1982 Aug;79(15):4766-9.
doi: 10.1073/pnas.79.15.4766.

Treatment of perennial allergic rhinitis by local hyperthermia

A Yerushalmi, S Karman, A Lwoff
Clinical Trial

Treatment of perennial allergic rhinitis by local hyperthermia

A Yerushalmi et al. Proc Natl Acad Sci U S A. 1982 Aug.

Abstract

Ninety-five patients with documented perennial allergic rhinitis have been treated with local hyperthermia of the nasal passages in a randomized double-blind trial. The treatment consisted of one series of three 30-min insufflations of humidified air at 43 degrees C at a 2-hr interval. In the active treatment group, 75% (P less than 0.00003) and 68% (P less than 0.00001) of the patients were free of symptoms 1 week and 1 month, respectively, after treatment, compared with a 28% and 17% response in the placebo group. We conclude that local hyperthermia is effective in the treatment of perennial allergic rhinitis.

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