Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1982;23(1):31-5.
doi: 10.1007/BF01061374.

Tizanidine in the treatment of spasticity

P M Newman, M Nogues, P K Newman, D Weightman, P Hudgson
Clinical Trial

Tizanidine in the treatment of spasticity

P M Newman et al. Eur J Clin Pharmacol. 1982.

Abstract

A double-blind crossover trial compared tizanidine with baclofen in 36 patients with spasticity. Tizanidine appeared to reduce lower limb spasticity more effectively and to have fewer side effects, but no statistically significant differences emerged when the two drugs were compared. An additional open study of tizanidine confirmed the beneficial action in a selected minority of patients with spasticity. This drug may have an important role in the management of spasticity, but further studies are required.

PubMed Disclaimer

References

    1. Nervenarzt. 1977 Jul;48(7):355-8 - PubMed
    1. Neurology. 1961 Aug;11:686-94 - PubMed
    1. J Neurol Neurosurg Psychiatry. 1980 Dec;43(12):1132-6 - PubMed
    1. Practitioner. 1964 Apr;192:540-2 - PubMed
    1. Acta Neurol Scand Suppl. 1965;13 Pt 2:557-8 - PubMed

Publication types

LinkOut - more resources