Treatment and relapse prophylaxis of duodenal ulcer with pirenzepine and cimetidine
- PMID: 6753114
Treatment and relapse prophylaxis of duodenal ulcer with pirenzepine and cimetidine
Abstract
The effect of pirenzepine and cimetidine on healing, symptoms and relapse rate of duodenal ulcer was studied in a placebo-controlled double-blind trial. Cimetidine (1 g daily) was superior at the beginning of therapy to a low dose of pirenzepine (75 mg daily) and placebo with regard to symptoms. No significant differences in ulcer healing were found between the 3 groups of treatment. The relapse rate after treatment with pirenzepine was lower than after treatment with cimetidine.
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