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Clinical Trial
. 1982:72:197-205.

Treatment and relapse prophylaxis of duodenal ulcer with pirenzepine and cimetidine

P M Eichenberger, M Giger, W Mattle, S Pelloni, S A Müller-Lissner, J J Gonvers, R Birchler, A L Blum
  • PMID: 6753114
Clinical Trial

Treatment and relapse prophylaxis of duodenal ulcer with pirenzepine and cimetidine

P M Eichenberger et al. Scand J Gastroenterol Suppl. 1982.

Abstract

The effect of pirenzepine and cimetidine on healing, symptoms and relapse rate of duodenal ulcer was studied in a placebo-controlled double-blind trial. Cimetidine (1 g daily) was superior at the beginning of therapy to a low dose of pirenzepine (75 mg daily) and placebo with regard to symptoms. No significant differences in ulcer healing were found between the 3 groups of treatment. The relapse rate after treatment with pirenzepine was lower than after treatment with cimetidine.

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