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. 1982;188(2):356-9.
doi: 10.1007/BF00332701.

Overlapping genes in the heat-labile enterotoxin operon originating from Escherichia coli human strain

T Yamamoto, T Tamura, T Yokota, T Takano

Overlapping genes in the heat-labile enterotoxin operon originating from Escherichia coli human strain

T Yamamoto et al. Mol Gen Genet. 1982.

Abstract

We have determined the nucleotide sequence at the distal end of the heat-labile enterotoxin subunit A (LT-A) gene (toxA) originating from human enterotoxigenic Escherichia coli. The sequenced region covers the entire LT-A2 region and a part of the LT-A1 region. In confirming our previous prediction based on product analysis of clones toxA regions, the data suggest the overlapping of the distal end (5'-TTA TGA) of toxA with the proximal end (5'-ATG AAT) of the LT subunit B gene (toxB), in the sequences 5'-TTATGAAT. Some additional characteristics of the LT operon as well as of the products are discussed.

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