Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1980 Mar;141(3):1291-7.
doi: 10.1128/jb.141.3.1291-1297.1980.

Beta-alanine synthesis in Escherichia coli

J E Cronan Jr

Beta-alanine synthesis in Escherichia coli

J E Cronan Jr. J Bacteriol. 1980 Mar.

Abstract

The enzyme, aspartate 1-decarboxylase (L-aspartate 1-carboxy-lyase; EC 4.1.1.15), that catalyzes the reaction aspartate leads to beta-alanine + CO2 was found in extracts of Escherichia coli. panD mutants of E. coli are defective in beta-alanine biosynthesis and lack aspartate 1-decarboxylase. Therefore, the enzyme functions in the biosynthesis of the beta-alanine moiety of pantothenate. The genetic lesion in these mutants is closely linked to the other pantothenate (pan) loci of E. coli K-12.

PubMed Disclaimer

References

    1. J Biol Chem. 1979 Aug 25;254(16):8074-82 - PubMed
    1. J Bacteriol. 1956 Aug;72(2):276-7 - PubMed
    1. Microbiol Rev. 1978 Jun;42(2):471-519 - PubMed
    1. Methods Enzymol. 1979;62:215-9 - PubMed
    1. J Biol Chem. 1956 Jan;218(1):97-106 - PubMed

Publication types

LinkOut - more resources