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. 1980 Mar;238(3):C127-32.
doi: 10.1152/ajpcell.1980.238.3.C127.

Effect of protein cross-linking reagents on membrane currents of squid axon

R Horn, M S Brodwick, D C Eaton

Effect of protein cross-linking reagents on membrane currents of squid axon

R Horn et al. Am J Physiol. 1980 Mar.

Abstract

The effects of the protein cross-linking reagents glutaraldehyde, tannic acid, and formaldehyde were examined in voltage-clamped and internally perfused squid axons. All three reagents reduced sodium and potassium currents and reduced or abolished sodium inactivation. Glutaraldehyde and tannic acid produced an alteration of potassium current kinetics.

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