This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!

Skip to main page content

Add to Collections

Your saved search

Name of saved search:

Search terms:

Test search terms

Would you like email updates of new search results?

Yes
No

Email: (change)

Frequency:

Which day?

Which day?

Report format:

Send at most:

Send even when there aren't any new results

Optional text in email:

Your RSS Feed

Clinical Trial

. 1980 Jan;17(1):71-7.

doi: 10.1007/BF00561679.

Pharmacokinetics of sodium valproate in epileptic patients: prediction of maintenance dosage by single-dose study

G J Schapel, R G Beran, C J Doecke, W J O'Reilly, P A Reece, R H Rischbieth, L N Sansom, P E Stanley

PMID: 6768573
DOI: 10.1007/BF00561679

Clinical Trial

Pharmacokinetics of sodium valproate in epileptic patients: prediction of maintenance dosage by single-dose study

G J Schapel et al. Eur J Clin Pharmacol. 1980 Jan.

. 1980 Jan;17(1):71-7.

doi: 10.1007/BF00561679.

Authors

G J Schapel, R G Beran, C J Doecke, W J O'Reilly, P A Reece, R H Rischbieth, L N Sansom, P E Stanley

PMID: 6768573
DOI: 10.1007/BF00561679

No abstract available

PubMed Disclaimer

Similar articles

Pharmacokinetics of enteric-coated valproic acid.
Albright PS, Bruni J, Suria D. Albright PS, et al. Ther Drug Monit. 1984;6(1):21-3. doi: 10.1097/00007691-198403000-00005. Ther Drug Monit. 1984. PMID: 6424275
Steady-state valproate pharmacokinetics during long term therapy.
Eadie MJ, Heazlewood V, McKauge L, Tyrer JH. Eadie MJ, et al. Clin Exp Neurol. 1983;19:183-91. Clin Exp Neurol. 1983. PMID: 6439443
Intra-dose variation in plasma protein binding of sodium valproate in epileptic patients.
Marty JJ, Kilpatrick CJ, Moulds RF. Marty JJ, et al. Br J Clin Pharmacol. 1982 Sep;14(3):399-404. doi: 10.1111/j.1365-2125.1982.tb01998.x. Br J Clin Pharmacol. 1982. PMID: 6812608 Free PMC article.
Clinical pharmacokinetics of sodium valproate, carbamazepine and phenytoin. Level-dose ration and interactions.
Levy RH, Moreland TA. Levy RH, et al. Schweiz Rundsch Med Prax. 1984 Feb 7;73(6):159-63. Schweiz Rundsch Med Prax. 1984. PMID: 6424205 Review. No abstract available.
Sodium valproate: a review of its pharmacological properties and therapeutic efficacy in epilepsy.
Pinder RM, Brogden RN, Speight TM, Avery GS. Pinder RM, et al. Drugs. 1977 Feb;13(2):81-123. doi: 10.2165/00003495-197713020-00001. Drugs. 1977. PMID: 402258 Review.

See all similar articles

Cited by

Clinical pharmacokinetics of antiepileptic drugs in paediatric patients. Part I: Phenobarbital, primidone, valproic acid, ethosuximide and mesuximide.
Battino D, Estienne M, Avanzini G. Battino D, et al. Clin Pharmacokinet. 1995 Oct;29(4):257-86. doi: 10.2165/00003088-199529040-00005. Clin Pharmacokinet. 1995. PMID: 8549027 Review.
The effects of peritoneal dialysis on the single dose and steady state pharmacokinetics of valproic acid in a uremic epileptic child.
Orr JM, Farrell K, Abbott FS, Ferguson S, Godolphin WJ. Orr JM, et al. Eur J Clin Pharmacol. 1983;24(3):387-90. doi: 10.1007/BF00610060. Eur J Clin Pharmacol. 1983. PMID: 6407847
Optimisation of antiepileptic drug therapy. The importance of serum drug concentration monitoring.
Yukawa E. Yukawa E. Clin Pharmacokinet. 1996 Aug;31(2):120-30. doi: 10.2165/00003088-199631020-00004. Clin Pharmacokinet. 1996. PMID: 8853934 Review.
A population pharmacokinetic model taking into account protein binding for the sustained-release granule formulation of valproic acid in children with epilepsy.
Rodrigues C, Chhun S, Chiron C, Dulac O, Rey E, Pons G, Jullien V. Rodrigues C, et al. Eur J Clin Pharmacol. 2018 Jun;74(6):793-803. doi: 10.1007/s00228-018-2444-2. Epub 2018 Mar 21. Eur J Clin Pharmacol. 2018. PMID: 29564480
First-dose and steady-state pharmacokinetics of valproic acid in children with seizures.
Hall K, Otten N, Irvine-Meek J, Leroux M, Budnick D, Verma M, Seshia SS. Hall K, et al. Clin Pharmacokinet. 1983 Sep-Oct;8(5):447-55. doi: 10.2165/00003088-198308050-00005. Clin Pharmacokinet. 1983. PMID: 6414752

References

1. Br Med J. 1975 Nov 1;4(5991):255-6 - PubMed
1. S Afr Med J. 1976 Nov 20;50(50):1997-8 - PubMed
1. Eur J Clin Pharmacol. 1975 Feb 28;8(2):97-105 - PubMed
1. Med Lett Drugs Ther. 1977 Nov 18;19(23):93-4 - PubMed
1. Br J Clin Pharmacol. 1978 Jun;5(6):495-9 - PubMed

Publication types

Actions
Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions

LinkOut - more resources

Full Text Sources
- Springer
Medical
- MedlinePlus Health Information