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. 1980;65(3):301-8.
doi: 10.1007/BF00493179.

Cytochemistry of the microtrabecular network in compact nucleoli of hepatocytes treated with cycloheximide

K Smetana, I Daskal, H Busch

Cytochemistry of the microtrabecular network in compact nucleoli of hepatocytes treated with cycloheximide

K Smetana et al. Histochemistry. 1980.

Abstract

Compact nucleoli without the segregation of nucleolar components were produced in hepatocytes by the treatment of experimental rats with cycloheximide to facilitate a cytochemical study on the organization of nucleolar components in such nucleoli. The extraction of pepsin pretreated specimens with nucleases (deoxyribonuclease and ribonuclease) demonstrated that compact nucleoli are characterized by a relatively uniform distribution of RNP components which mask a microtrabecular intranucleolar network. This network apparently consists of proteins and contains fine DNA filaments.

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References

    1. J Ultrastruct Res. 1969 Oct;29(1):1-14 - PubMed
    1. Stain Technol. 1964 Mar;39:111-4 - PubMed
    1. C R Acad Sci Hebd Seances Acad Sci D. 1975 Sep 29;281(13):901-3 - PubMed
    1. J Electron Microsc (Tokyo). 1973;22(2):205-16 - PubMed
    1. J Cell Biol. 1977 Jun;73(3):616-37 - PubMed