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. 1980 Mar 24;290(12):791-3.

[Dexamethasone regulation of the prolactin release induced by vasoactive intestinal peptide (VIP)]

[Article in French]
  • PMID: 6769606

[Dexamethasone regulation of the prolactin release induced by vasoactive intestinal peptide (VIP)]

[Article in French]
W Rotsztejn et al. C R Seances Acad Sci D. .

Abstract

The regulation of prolactin (PRL) secretion induced by the vasoactive intestinal peptide (VIP) has been studied on purified male Rat Pituitary PRL cells obtained by means of velocity sedimentation at unit gravity. Dexamethasone (10(-9) M) in the incubation medium inhibits the stimulatory effect of VIP (10(-7) M) on PRL release. This result suggests that glucocorticoids play an important role in the regulation of VIP effects at the effects at the pituitary level.

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