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Comparative Study
. 1980 Apr;12(4):391-5.
doi: 10.1111/j.1365-2265.1980.tb02726.x.

Sex hormone changes in male epileptics

B K Toone, M Wheeler, P B Fenwick
Comparative Study

Sex hormone changes in male epileptics

B K Toone et al. Clin Endocrinol (Oxf). 1980 Apr.

Abstract

Mean plasma levels of LH, FSH, PRL, and sex-hormone binding globulin (SHBG) were raised in twenty-seven epileptics on anticonvulsants compared with age matched controls. Sexual activity appeared to be reduced. Anticonvulsant therapy results in raised SHBG levels which may be associated with a lowered free testosterone level as indicated by raised LH levels and lowered sexual activity.

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