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. 1980 Mar 31;290(13):879-82.

[Correlation between the loss of plasmid DNA and the transition from virulent phase I to avirulent phase II in Shigella sonnei]

[Article in French]
P Sansonetti, M David, M Toucas
  • PMID: 6771038

[Correlation between the loss of plasmid DNA and the transition from virulent phase I to avirulent phase II in Shigella sonnei]

[Article in French]
P Sansonetti et al. C R Seances Acad Sci D. .

Abstract

Transition from virulent phase I to non virulent phase II in five strains of Shigella sonnei was studied by immunofluorescence and plasmid electrophoresis. High frequency loss of phase I specific antigens was observed by use of fluorescent phase specific antibodies. Agarose gel electrophoresis of bacterial lysates showed that transition from phase I to phase II is associated with the loss of extrachromosomal DNA.

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