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. 1978 May;30(3):262-70.

Ethnic variation of genetic disease: roles of drift for recessive lethal genes

D Wagener, L L Cavalli-Sforza, R Barakat

Ethnic variation of genetic disease: roles of drift for recessive lethal genes

D Wagener et al. Am J Hum Genet. 1978 May.

Abstract

Using Wright's distribution of gene frequencies for a recessive lethal gene, a method is given to analyze the probability that any particular gene frequency is greater than a given threshold gene frequency. The method is introduced to analyze the plausibility of drift for explaining observed data.

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References

    1. Proc Natl Acad Sci U S A. 1937 Jun;23(6):307-20 - PubMed
    1. J Pediatr. 1957 Jul;51(1):58-64 - PubMed
    1. Am J Hum Genet. 1975 May;27(3):348-64 - PubMed
    1. Soc Biol. 1977 Summer;24(2):117-34 - PubMed
    1. Am J Hum Genet. 1973 Nov;25(6):594-7 - PubMed

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