doi: 10.1007/BF00270501.
Butyrate suppression of position-effect variegation in Drosophila melanogaster
- PMID: 6771490
- DOI: 10.1007/BF00270501
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Butyrate suppression of position-effect variegation in Drosophila melanogaster
Mol Gen Genet.
1980.
Abstract
The strain of Drosophila melanogaster carrying the inversion of In(1)wm4, which juxtaposes the normal w+ gene to the centromeric heterochromatin, variegages for pigmentation in the eye. This strain was treated with various concentrations of n-butyrate and n-proprionate during the embryonic and larval stages. Concentrations as low as 70 mM markedly suppress the variegated eye phenotype. This suggests that non-acetylated histones play a major role in the phenomenon of position-effect variegation.
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