[Selective inhibition of the fluorescence of benzo(a)pyrene and a mutagenic diol-epoxide derivative in living cells by liposoluble iodinated hydrocarbons]
[Article in
French]
- PMID: 6772331
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[Selective inhibition of the fluorescence of benzo(a)pyrene and a mutagenic diol-epoxide derivative in living cells by liposoluble iodinated hydrocarbons]
[Article in
French]
C R Seances Acad Sci D.
.
Abstract
It is shown that in living cells, some liposoluble collisional quenchers like n-iodo hexane and iodo benzene can be used to selectively quench the benzo(a)pyrene fluorescence, leving the diol-epoxide benzo(a)pyrene metabolite emission. The preferential solubilities of these compounds, fluorophors and quenchers, explain the results and the fluorophor location.