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. 1980 Sep;16(9):775-80.
doi: 10.1007/BF02619312.

Biological and biochemical properties of a human uveal melanocyte-derived cell line

F L Meyskens Jr, E B Berglund, D F Saxe, B B Fuller, L Z Pacelli, J D Hall, C G Ray
Free article

Biological and biochemical properties of a human uveal melanocyte-derived cell line

F L Meyskens Jr et al. In Vitro. 1980 Sep.
Free article

Abstract

A human uveal melanocyte-derived cell line (U1I) is described. The cell line has a doubling time of 27.2 hr, a plating efficiency on plastic surfaces of 10%, and a cloning efficiency in soft agar of < 0.1%. U1I displays marked chromosomal aneuploidy and sensitivity to ultraviolet light. Biochemical studies indicate the presence of tyrosinase, which is stimulated by several compounds, including theophylline, progesterone, and nerve growth factor.

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