doi: 10.1038/286669a0.
An immunoglobulin deletion mutant with implications for the heavy-chain switch and RNA splicing
- PMID: 6774257
- DOI: 10.1038/286669a0
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An immunoglobulin deletion mutant with implications for the heavy-chain switch and RNA splicing
Nature.
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Abstract
The IF2 immunoglobulin mutant is a DNA deletion of one coding segment and large sections of the flanking intervening sequences. The deletion results in a new splicing pattern and starts in a DNA region containing tandemly repeated sequences which may carry heavy-chain class switch signals.
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