[Acetylcholinesterase and monoamine oxidase activity in hypothalamic structures during water deprivation]

Abstract

Light, electron microscopy and cytospectrophatometry were used to study the level of acetylcholinesterase and monoamine oxidase in the hypothalamus nuclei during different periods of water deprivation in white rats. It was demonstrated that depending upon the time of deprivation, there is a successive triggering of the cholino- adrenoreactive systems in the hypothalamus. However, the main role in the perception of water deprivation in the triggering of the regulatory mechanisms is played by the cholinergic mediator system in the lateral preoptic area, lateral and supraoptical nuclei of the hypothalamus.