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. 1980 Oct 15;36(10):1213-5.
doi: 10.1007/BF01976136.

Histopathological modifications following immunotherapy with P 40 in rats bearing DMBA-induced mammary carcinoma

K H Hollmann, J M Verley

Histopathological modifications following immunotherapy with P 40 in rats bearing DMBA-induced mammary carcinoma

K H Hollmann et al. Experientia. .

Abstract

Female Sprague-Dawley rats bearing primarily-induced mammary carcinomas were treated with a new immunostimulating agent (P 40). The histopathological modifications encountered in tumors, lymph nodes, liver and spleen are described. Intratumoral injections provoke a more widespread response of the RES, and particularly a more intense reaction in the draining lymph nodes, than systemic treatment.

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