Effects of thyrotrophic-releasing hormone (TRH) on thermoregulation in the rat
- PMID: 6774889
- DOI: 10.1007/BF01965979
Effects of thyrotrophic-releasing hormone (TRH) on thermoregulation in the rat
Abstract
At ambient temperatures (Ta) of both 8 and 22 degrees C, intraventricular administration of TRH (10-80 microgram) produced a dose-dependent hypothermia in rats. The hypothermia was due to both decreased metabolic heat production and cutaneous vasodilatation. In contrast, at 30 degrees C Ta, TRH increased metabolic heat production (due to behavioral excitation) and led to hyperthermia.
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