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. 1980 Sep 15;36(9):1077-8.
doi: 10.1007/BF01965979.

Effects of thyrotrophic-releasing hormone (TRH) on thermoregulation in the rat

M T Lin, A Chandra, Y F Chern, B L Tsay

Effects of thyrotrophic-releasing hormone (TRH) on thermoregulation in the rat

M T Lin et al. Experientia. .

Abstract

At ambient temperatures (Ta) of both 8 and 22 degrees C, intraventricular administration of TRH (10-80 microgram) produced a dose-dependent hypothermia in rats. The hypothermia was due to both decreased metabolic heat production and cutaneous vasodilatation. In contrast, at 30 degrees C Ta, TRH increased metabolic heat production (due to behavioral excitation) and led to hyperthermia.

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