doi: 10.1002/j.1552-4604.1980.tb02544.x.
Albumin-binding interactions of sodium valproate
- PMID: 6776162
- DOI: 10.1002/j.1552-4604.1980.tb02544.x
Item in Clipboard
Albumin-binding interactions of sodium valproate
J Clin Pharmacol.
1980 Aug-Sep.
Abstract
In vitro equilibrium dialysis experiments show that salicylate and phenylbutazone displace valproate from its binding sites on human serum albumin at therapeutic concentrations, whereas warfarin and carbamazepin do not.
Similar articles
-
Drug interactions with valproic acid.Drugs. 1982 Dec;24(6):543-56. doi: 10.2165/00003495-198224060-00004. Drugs. 1982. PMID: 6818015 Review.
-
Effect of valproic acid, its unsaturated metabolites and some structurally related fatty acids on the binding of warfarin and dansylsarcosine to human albumin.Biochem Pharmacol. 1991 Apr 15;41(8):1227-33. doi: 10.1016/0006-2952(91)90662-o. Biochem Pharmacol. 1991. PMID: 1706921
-
An in vitro study of drug displacement interactions: warfarin-salicylate and warfarin-phenylbutazone.J Pharm Pharmacol. 1979 May;31(5):322-30. doi: 10.1111/j.2042-7158.1979.tb13509.x. J Pharm Pharmacol. 1979. PMID: 37303
-
Cooperative interaction of warfarin and phenylbutazone with human serum albumin.Biochem Pharmacol. 1981 Jun 1;30(11):1169-73. doi: 10.1016/0006-2952(81)90293-8. Biochem Pharmacol. 1981. PMID: 7271816 No abstract available.
-
Application of stable labelled drugs in clinical pharmacokinetic investigations.Clin Pharmacokinet. 1982 Nov-Dec;7(6):490-507. doi: 10.2165/00003088-198207060-00002. Clin Pharmacokinet. 1982. PMID: 6819104 Review. No abstract available.
Cited by
-
Drug interactions with valproic acid.Drugs. 1982 Dec;24(6):543-56. doi: 10.2165/00003495-198224060-00004. Drugs. 1982. PMID: 6818015 Review.
-
Treating epilepsy in the elderly: safety considerations.Drug Saf. 2001;24(13):991-1015. doi: 10.2165/00002018-200124130-00006. Drug Saf. 2001. PMID: 11735655 Review.
-
Clinical Consequences of Disproportionate Free Valproate Elevation in Critically Ill Adult Patients: A Multicenter Retrospective Cohort Study.Neurocrit Care. 2025 Mar 25:10.1007/s12028-025-02243-y. doi: 10.1007/s12028-025-02243-y. Online ahead of print. Neurocrit Care. 2025. PMID: 40133756
-
Pharmacokinetic interactions with antiepileptic drugs.Clin Pharmacokinet. 1982 Jan-Feb;7(1):57-84. doi: 10.2165/00003088-198207010-00004. Clin Pharmacokinet. 1982. PMID: 7042173 Review.
-
Antiepileptic drugs. A review of clinically significant drug interactions.Drug Saf. 1993 Sep;9(3):156-84. doi: 10.2165/00002018-199309030-00003. Drug Saf. 1993. PMID: 8240723 Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
