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. 1980 Aug-Sep;20(8-9):514-7.
doi: 10.1002/j.1552-4604.1980.tb02544.x.

Albumin-binding interactions of sodium valproate

J S Fleitman, J Bruni, J H Perrin, B J Wilder

Albumin-binding interactions of sodium valproate

J S Fleitman et al. J Clin Pharmacol. 1980 Aug-Sep.

Abstract

In vitro equilibrium dialysis experiments show that salicylate and phenylbutazone displace valproate from its binding sites on human serum albumin at therapeutic concentrations, whereas warfarin and carbamazepin do not.

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