Effect of treatment of malignant disease on growth in children
- PMID: 6776906
- PMCID: PMC1627054
- DOI: 10.1136/adc.55.8.600
Effect of treatment of malignant disease on growth in children
Abstract
The growth of 95 children with malignant disease was studied over a 3- or 4-year period, and compared with the growth of normal children matched for age and sex by calculation of the standard deviation score. The mean standard deviation score of the children with leukaemia fell in the first year of treatment, and thereafter showed little change, remaining below the normal. This effect was related to cranial and craniospinal irradiation, but not to age or duration of chemotherapy. The loss in eventual height attained was small and does not suggest any long-term interference with growth hormone production.
Similar articles
-
Growth and puberty after growth hormone treatment after irradiation for brain tumours.Arch Dis Child. 1995 Aug;73(2):141-6. doi: 10.1136/adc.73.2.141. Arch Dis Child. 1995. PMID: 7574858 Free PMC article.
-
Growth and growth hormone status following treatment for childhood leukaemia.Horm Res. 1998;50(1):1-10. doi: 10.1159/000023193. Horm Res. 1998. PMID: 9691206 Review.
-
Prophylactic cranial irradiation of acute lymphoblastic leukemia in childhood: outcomes of late effects on pituitary function and growth in long-term survivors.Int J Cancer. 2001;96 Suppl:117-24. doi: 10.1002/ijc.10348. Int J Cancer. 2001. PMID: 11992395
-
[Statural growth following irradiation of the central nervous system for medulloblastoma of the posterior fossa. Retrospective analysis of 45 cases].Arch Fr Pediatr. 1985 Mar;42(3):219-23. Arch Fr Pediatr. 1985. PMID: 4004484 French.
-
[Late endocrine and growth sequelae after cancer treatment in children].Ugeskr Laeger. 1994 Aug 8;156(32):4559-61, 4564-5. Ugeskr Laeger. 1994. PMID: 7832924 Review. Danish.
Cited by
-
Abnormalities of growth and gonadal function in children treated for malignant disease: a review.J R Soc Med. 1982 Aug;75(8):641-7. doi: 10.1177/014107688207500812. J R Soc Med. 1982. PMID: 7050380 Free PMC article. Review. No abstract available.
-
Weight gain and height velocity during prolonged first remission from acute lymphoblastic leukaemia.Arch Dis Child. 1985 Sep;60(9):832-6. doi: 10.1136/adc.60.9.832. Arch Dis Child. 1985. PMID: 3863545 Free PMC article.
-
Spinal growth after irradiation for Wilm's tumour.Int Orthop. 1991;15(4):387-91. doi: 10.1007/BF00186885. Int Orthop. 1991. PMID: 1667185
-
The comprehensive assessment of health status in survivors of childhood cancer: application to high-risk acute lymphoblastic leukaemia.Br J Cancer. 1993 May;67(5):1047-52. doi: 10.1038/bjc.1993.192. Br J Cancer. 1993. PMID: 8494697 Free PMC article.
-
Height and lymphoblastic leukaemia.Arch Dis Child. 1983 Apr;58(4):300-1. doi: 10.1136/adc.58.4.300. Arch Dis Child. 1983. PMID: 6573871 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical