[The influence on mood and performance in healthy subjects by lithium carbonate (author's transl)]

Abstract

Lithium carbonate was administered during a double-blind crossover experiment lasting 8 weeks, involving 11 healthy volunteers. In psychological tests, no deterioration in mood, performance or memory could be shown. Informal diary entries made by the subjects, however, refer to complaints, particularly relating to vegetative functions, more frequently under lithium medication than during the placebo period. In the interpretation of the findings, it is important to take into account the very high motivation of the subjects.