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. 1980;72(1):109-10.
doi: 10.1007/BF00433815.

Amphetamine stereotypies and polyribosomal disaggregation in rats: effects of adrenergic and serotonergic blocking agents

M M Widelitz, C P Hable 2nd

Amphetamine stereotypies and polyribosomal disaggregation in rats: effects of adrenergic and serotonergic blocking agents

M M Widelitz et al. Psychopharmacology (Berl). 1980.

Abstract

To find the specific chemical moiety responsible for the disaggregation of polyribosomes after induction of aberrant behavior by d-amphetamine, specific amine blockers and reserpine were utilized. It appears that dopamine is responsible for both the disaggregation of polyribosomes and stereotypic behavior while the roles of serotonin and norepinephrine are not significant in this system.

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