Algorithms for calculating and correcting blood-gas and acid-base variables
- PMID: 6784207
- DOI: 10.1016/0034-5687(80)90116-4
Algorithms for calculating and correcting blood-gas and acid-base variables
Abstract
This is a review of the origins, derivations, and 'fidelity' of available equations for correcting PO2, PCO2, and pH for temperature, and for estimating blood-gas and acid-base variables from measured values: 1. Oxygen saturation (SO2) from PO2, PCO2, pH, and body temperature (T). 2. Oxygen concentration (CO2) from SO2, PO2, and hemoglobin concentration (Hb). 3. Base excess (BE) from pH, PCO2, and Hb. 4. 'In vivo BE' (BE3) from pH and PCO2. 5. 'Compensated BE3' (BEC) from PCO2. 6. Bicarbonate ([HCO3-]) and carbon dioxide concentrations (CCO2) from pH and PCO2. PHysiologic considerations are emphasized, with mathematical background when it contributes to understanding. Algorithms are variously compared with their graphic counterparts, with the data from which they were derived, and with each other.
Similar articles
-
A program for calculation of intrapulmonary shunts, blood-gas and acid-base values with a programmable calculator.Anesthesiology. 1975 Jan;42(1):88-95. doi: 10.1097/00000542-197501000-00013. Anesthesiology. 1975. PMID: 234212
-
[Base excess] and [strong ion difference] during O2-CO2 exchange.Adv Exp Med Biol. 1997;411:97-102. doi: 10.1007/978-1-4615-5865-1_12. Adv Exp Med Biol. 1997. PMID: 9269416
-
Nomograms for correction of blood Po2, Pco2, pH, and base excess for time and temperature.J Appl Physiol. 1966 Sep;21(5):1484-90. doi: 10.1152/jappl.1966.21.5.1484. J Appl Physiol. 1966. PMID: 5923219 No abstract available.
-
Blood acid-base state at a variable temperature. A graphical representation.Respir Physiol. 1977 Nov;31(2):259-75. doi: 10.1016/0034-5687(77)90108-6. Respir Physiol. 1977. PMID: 22117 Review.
-
Sampling and storage of blood for pH and blood gas analysis.J Am Vet Med Assoc. 1977 Feb 15;170(4):429-33. J Am Vet Med Assoc. 1977. PMID: 14093 Review.
Cited by
-
Individualised pulse oximetry limits in neonatal intensive care.Arch Dis Child Fetal Neonatal Ed. 1999 Nov;81(3):F194-6. doi: 10.1136/fn.81.3.f194. Arch Dis Child Fetal Neonatal Ed. 1999. PMID: 10525022 Free PMC article.
-
Benefits and risks of the P/F approach.Intensive Care Med. 2018 Dec;44(12):2245-2247. doi: 10.1007/s00134-018-5413-4. Epub 2018 Oct 23. Intensive Care Med. 2018. PMID: 30353385 No abstract available.
-
The cardiovascular sparing effect of fentanyl and atropine, administered to enflurane anesthetized dogs.Can J Vet Res. 1994 Oct;58(4):248-53. Can J Vet Res. 1994. PMID: 7889455 Free PMC article.
-
Pulmonary gas exchange and acid-base balance during exercise.Compr Physiol. 2013 Apr;3(2):693-739. doi: 10.1002/cphy.c110048. Compr Physiol. 2013. PMID: 23720327 Free PMC article. Review.