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. 1980 Dec 8;291(12):937-40.

[Secondary and topographic structure of ribosomal RNA 16S of Escherichia coli]

[Article in French]
P Stiegler, P Carbon, M Zuker, J P Ebel, C Ehresmann
  • PMID: 6784944

[Secondary and topographic structure of ribosomal RNA 16S of Escherichia coli]

[Article in French]
P Stiegler et al. C R Seances Acad Sci D. .

Abstract

We present a model for the secondary structure of 16S ribosomal RNA from E. coli. This model has been deduced by restricting the total number of theoretical base pairings using the following criteria: (1) susceptibility of residues towards enzymatic probes that are specific for either paired or single stranded regions; (2) reactivity of certain residues to chemical modification; (3) evidence for medium and long range interactions; (4) comparative analysis of ribosomal RNA sequences from other organisms.

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