Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1981;82(2):249-57.
doi: 10.1007/BF00286109.

Mutants partially defective in excision repair at five autosomal loci in Drosophila melanogaster

J B Boyd, P V Harris

Mutants partially defective in excision repair at five autosomal loci in Drosophila melanogaster

J B Boyd et al. Chromosoma. 1981.

Abstract

Primary cell cultures derived from mutants in seventeen different genes were analyzed for their ability to excise pyrimidine dimers from DNA. Five of these mutagen-sensitive mutants [mus(2)205A1, mus(3)302D1, mus(3)304D3, mus(3)306D1, mus(3)308D2] display a significantly reduced excision capacity relative to control cultured. In addition, two of the five [mus(3)306D2, mus(3)308D2] are defective in the accumulation of single-strand breaks normally seen after ultraviolet irradiation. This study, therefore, brings the total number of Drosophila mutants known to be defective in excision repair to seven. The results are discussed relative to other genetic and biochemical properties of these mutants.

PubMed Disclaimer

References

    1. Proc Natl Acad Sci U S A. 1964 Feb;51:226-31 - PubMed
    1. Biochim Biophys Acta. 1980 Nov 14;610(1):116-29 - PubMed
    1. Biochemistry. 1976 Oct 19;15(21):4629-37 - PubMed
    1. Biochim Biophys Acta. 1960 Jul 15;41:550-1 - PubMed
    1. Proc Natl Acad Sci U S A. 1976 Nov;73(11):4140-4 - PubMed

Publication types

Substances

LinkOut - more resources