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. 1978 Jul-Aug;23(4):645-8.

[Dipole cooperative model of ion channels of excitable biomembranes. Conductance of ion channels]

[Article in Russian]
  • PMID: 678572

[Dipole cooperative model of ion channels of excitable biomembranes. Conductance of ion channels]

[Article in Russian]
V F Pastushenko et al. Biofizika. 1978 Jul-Aug.

Abstract

An analysis of ionic channel conductance is presented in terms of dipole cooperative model. The dependence of conductance on displaced charge is found to be an S-shaped function. Basing on this function and kinetics of gating currents, the kinetic curves for the conductance are calculated. These curves are compared with Hodgkin--Huxley results on sodium channel. A good agreement may be observed for the case of positive jumps of the potential. Less accurate coincidence takes place for negative jumps of the potential.

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