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. 1981;73(2):184-7.
doi: 10.1007/BF00429215.

Clozapine: plasma levels and prolactin response

J M Kane, T B Cooper, E J Sachar, F S Halpern, S Bailine

Clozapine: plasma levels and prolactin response

J M Kane et al. Psychopharmacology (Berl). 1981.

Abstract

Serial plasma clozapine levels and serum prolactin levels were determined in two schizophrenic patients receiving clozapine, a novel antipsychotic drug. Despite marked therapeutic response and substantial clozapine blood levels, prolactin levels obtained 11--12 h after the last oral dose were unaffected or only minimally elevated. This confirms previous evidence of clozapine's unusual characteristics.

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