Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1981 May 30;282(6278):1747-8.
doi: 10.1136/bmj.282.6278.1747.

Malaria diagnosis by enzyme-linked immunosorbent assays

D E Bidwell, A Voller

Malaria diagnosis by enzyme-linked immunosorbent assays

D E Bidwell et al. Br Med J (Clin Res Ed). .

Abstract

Enzyme-linked immunosorbent assays (ELISA) for detecting malarial parasites in blood were tested on uninfected monkeys and in monkeys infected with Plasmodium falciparum. A double antibody sandwich ELISA detected one malarial cell per 10(3) uninfected cells, and an inhibition ELISA detected on infected cell per 10(4) uninfected erythrocytes. These methods are not yet as sensitive as conventional blood-film examinations, in which a well-trained microscopist might be expected to detect one malarial cell per 10(6) erythrocytes. Nevertheless, ELISA offers an objective means of detecting malaria and is particularly advantageous since up to 100 samples may be processed simultaneously.

PubMed Disclaimer

References

    1. Trans R Soc Trop Med Hyg. 1970;64(4):547-54 - PubMed
    1. Bull World Health Organ. 1980;58(3):439-44 - PubMed
    1. Parasitology. 1980 Feb;80(1):171-82 - PubMed
    1. Trans R Soc Trop Med Hyg. 1976;70(2):98-106 - PubMed

Publication types

LinkOut - more resources