[Analysis of the stability and local cooperativity of DNA : elements permitting the recognition of promoters by DNA-dependent RNA polymerase]
- PMID: 6786772
[Analysis of the stability and local cooperativity of DNA : elements permitting the recognition of promoters by DNA-dependent RNA polymerase]
Abstract
Analysis of the local stability of promoters processed by E. Coli RNA polymerase shows that they bear a characteristic stability profile: two segments of low stability are located around --35 and --8 bases ahead of the transcription start and are generally bordered by more stable segments. This key profile may act as a recognition signal for both attracting and positioning the RNA polymerase in the promoter site.
Similar articles
-
Promoter recognition and transcription initiation in E. coli.Folia Biol (Praha). 1984;30 Spec No:105-18. Folia Biol (Praha). 1984. PMID: 6373393
-
[Analysis of the stability and local cooperativity of DNA: proposal of a molecular mechanism for the initiation of the transcription of gene A3 of bacteriophage T7 by the RNA polymerase from E. coli].C R Seances Acad Sci III. 1981 Jan 12;292(2):177-80. C R Seances Acad Sci III. 1981. PMID: 6783340 French.
-
Domain 1.1 of the sigma(70) subunit of Escherichia coli RNA polymerase modulates the formation of stable polymerase/promoter complexes.J Mol Biol. 2001 Jun 8;309(3):561-72. doi: 10.1006/jmbi.2001.4690. J Mol Biol. 2001. PMID: 11397080
-
Protein-protein interactions during transcription activation: the case of the Escherichia coli cyclic AMP receptor protein.Philos Trans R Soc Lond B Biol Sci. 1996 Apr 29;351(1339):543-50. doi: 10.1098/rstb.1996.0053. Philos Trans R Soc Lond B Biol Sci. 1996. PMID: 8735277 Review.
-
[Interaction of bacterial RNA polymerase with the promotor region].Postepy Biochem. 1982;28(4):465-86. Postepy Biochem. 1982. PMID: 6764808 Review. Polish. No abstract available.
Cited by
-
DNA sequences specifying the transcription of the streptococcal kanamycin resistance gene in Escherichia coli and Bacillus subtilis.Mol Gen Genet. 1985;198(2):348-52. doi: 10.1007/BF00383017. Mol Gen Genet. 1985. PMID: 3920478