Detection and measurement of fetomaternal haemorrhage: serum alpha-fetoprotein and the Kleihauer technique
- PMID: 67873
- PMCID: PMC1606867
- DOI: 10.1136/bmj.1.6073.1377
Detection and measurement of fetomaternal haemorrhage: serum alpha-fetoprotein and the Kleihauer technique
Abstract
A raised maternal serum alpha-fetoprotein concentration was taken as an indicator of fetomaternal haemorrhage due to amniocentesis and was used to calculate the volume of the fetal bleed. The alpha-fetoprotein concentration seemed to be a more sensitive and reliable indicator than the established Kleihauer technique and may have further applications in antenatal testing.
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