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. 1981 Jul 1;154(1):204-9.
doi: 10.1084/jem.154.1.204.

Enhancement of delayed hypersensitivity reaction with varieties of anti-cancer drugs. A common biological phenomenon

M Goto, A Mitsuoka, M Sugiyama, M Kitano

Enhancement of delayed hypersensitivity reaction with varieties of anti-cancer drugs. A common biological phenomenon

M Goto et al. J Exp Med. .

Abstract

Delayed hypersensitivity reaction in mice was commonly enhanced with various anti-cancer agents administered as single or intermittent high doses but not consecutive divided doses. The effect of anti-cancer agents on the delayed hypersensitivity reaction was thought to be due to elimination of suppressor T cell activity.

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