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Clinical Trial
. 1981;73(4):359-62.
doi: 10.1007/BF00426466.

Reserpine and alpha-methyldopa in the treatment of tardive dyskinesia

C C Huang, R I Wang, A Hasegawa, L Alverno
Clinical Trial

Reserpine and alpha-methyldopa in the treatment of tardive dyskinesia

C C Huang et al. Psychopharmacology (Berl). 1981.

Abstract

Thirty inpatients with evidence of tardive dyskinesia secondary to antipsychotic medications participated in this double-blind, controlled, randomized study comparing reserpine, alpha-methyldopa and placebo. Reserpine at doses of 0.75--1.5 mg daily, or alpha-methyldopa at doses of 750--1,500 mg daily, produced a statistically significant improvement in tardive dyskinesia symptomatology compared to the results obtained with placebo.

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