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Case Reports
. 1981 Jul;124(1):94-6.
doi: 10.1164/arrd.1981.124.1.94.

Selective immunoglobulin G4 deficiency and recurrent infections of the respiratory tract

C S Beck, D C Heiner
Case Reports

Selective immunoglobulin G4 deficiency and recurrent infections of the respiratory tract

C S Beck et al. Am Rev Respir Dis. 1981 Jul.

Abstract

Using a newly developed radioimmunoassay, 4 of 422 subjects tested were found to have an isolated absence of the immunoglobulin subclass IgG4. All had severe recurrent sinopulmonary infection. The association of these disorders with an isolated absence of IgG4 suggested that this immunoglobulin subclass may have a unique role in host respiratory tract defense mechanisms.

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