Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1981 Jul;78(7):4256-60.
doi: 10.1073/pnas.78.7.4256.

Pyochelin: novel structure of an iron-chelating growth promoter for Pseudomonas aeruginosa

C D Cox, K L Rinehart Jr, M L Moore, J C Cook Jr

Pyochelin: novel structure of an iron-chelating growth promoter for Pseudomonas aeruginosa

C D Cox et al. Proc Natl Acad Sci U S A. 1981 Jul.

Abstract

Pyochelin, an endogenous growth promoter that solubilizes ferric iron, has been isolated from Pseudomonas aeruginosa, including clinical strains. The structure of pyochelin has been assigned as 2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid and is of a different type from those previously assigned to siderophores (siderochromes) from bacteria. The assignment rests on 1H and 13C NMR data, high-resolution (including field desorption) mass spectrometry, and spectroscopic properties of synthetic model compounds. Pyochelin is presumed to be biosynthesized from salicylic acid and two moles of cysteine.

PubMed Disclaimer

References

    1. Arch Mikrobiol. 1968;60(4):326-39 - PubMed
    1. Biochem Biophys Res Commun. 1970 Mar 12;38(5):989-92 - PubMed
    1. Bacteriol Rev. 1970 Jun;34(2):99-125 - PubMed
    1. Biochim Biophys Acta. 1970 Aug 14;215(2):393-402 - PubMed
    1. J Infect Dis. 1974 Nov;130 Suppl(0):S8-13 - PubMed

Publication types

MeSH terms

LinkOut - more resources