Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1981;66(1):19-26.
doi: 10.1159/000207086.

Chromatographic fractionation of anti-sickling agents in Fagara xanthoxyloides

S Abu, S Anyaibe, V Headings

Chromatographic fractionation of anti-sickling agents in Fagara xanthoxyloides

S Abu et al. Acta Haematol. 1981.

Abstract

Fractionation of an aqueous extract of root bark from Fagara xanthoxyloides by column chromatography on DEAE-A-50, utilizing an elution gradient of pH 7.5-5.0, yielded five fractions. All fractions reversed metabisulfite-induced sickling in vitro of erythrocytes homozygous for hemoglobin S. Only the fraction containing the least anti-sickling activity also contained alkaloids. Thin-layer chromatography on silica gel and aluminum oxide revealed further molecular heterogeneity within two of the fractions.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources