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Clinical Trial
. 1976;4(2 Suppl):58-67.

The measurement of pain in terminal carcinoma

  • PMID: 67975
Clinical Trial

The measurement of pain in terminal carcinoma

R G Twycross. J Int Med Res. 1976.

Abstract

1. A method is described for comparing narcotic analgesics and adjuvants in patients with terminal cancer. 2. A randomized controlled trial of orally administered diamorphine and morphine is reported to illustrate the method. 3. It is concluded that there is no over-all clinical difference between diamorphine and morphine when administered by mouth every four hours at individually optimized doses in association with cocaine and a phenothiazine. 4. The validity, reliability and sensitivity of the method are discussed.

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