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. 1981 Aug 15;28(2):237-40.
doi: 10.1002/ijc.2910280218.

Mapping of the Fv-4 mouse gene controlling resistance to murine leukemia viruses

Mapping of the Fv-4 mouse gene controlling resistance to murine leukemia viruses

H Ikeda et al. Int J Cancer. .

Abstract

Fv-4, a gene controlling susceptibility to ecotropic murine leukemia viruses, was linked to both Pre-I (prealbumin) and Igh-I (immunoglobulin heavy-chain constant region) loci on chromosome 12 in mice. The gene order was Fv-4 - Pre-I - Igh-I, and the estimated frequency of recombination between Fv-4 and Pre-I was about 20%.

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