Evidence for the presence of choleragen receptor on the thymocyte-brain antigen molecule of mice
- PMID: 67998
- PMCID: PMC1445331
Evidence for the presence of choleragen receptor on the thymocyte-brain antigen molecule of mice
Abstract
CBA thymocytes were subjected to cocapping experiments using AThy-1.2 and choleragen. The finding that both structures showed a common ligant-induced redistribution implies that choleragen receptors of the cell membrane are associated with the thymocyte-brain molecule. Furthermore, it was found that the thymocyte-brain antigenic determinants on the thymocyte were not blocked by prior choleragen treatment. This suggests a spatial distance between these structures on the molecule.
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