Mycoplasma pneumoniae infection: role of a surface protein in the attachment organelle
- PMID: 6801766
- DOI: 10.1126/science.6801766
Mycoplasma pneumoniae infection: role of a surface protein in the attachment organelle
Abstract
Attachment of Mycoplasma pneumoniae to host cell by means of a specialized terminus initiates infection. Monoclonal antibodies to a surface protein (Pl) inhibit this process, and react with a region of the tip covered with peplomer-like particles. Since antibodies against the Pl protein are generated by natural and experimental infection and by immunization, the substance may be an important determinant of protective immunity.
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